Provisional Agenda
(Subject to change)
Day 0: Tuesday 27th August
1900-2200: The pre-conference social meet-up will be at 1900h at Angel and Greyhound in St Clement’s Street, a few minutes’ walk from St Hilda’s College.
Day 1: Wednesday 28th August
0745: Registration, welcome coffee and networking
0820: Welcome and housekeeping
Session 1: Omics in Toxinology – Chair Dr Eddie Rowan
0830: Professor Juan Calvete – keynote
Evolutionary and Translational Venomics Laboratory, Consejo Superior de Investigaciones Científicas (CSIC), Valencia, Spain
Phylovenomics of daboia russelii across the indian subcontinent. Bioactivities and comparative in vivo neutralization and in vitro 3G antivenomics of antivenoms against venoms from India, Bangladesh and Sri Lanka
0900: Dr Timothy Jenkins
Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
The unlocked potential of venom gland transcriptomics, droplet microfluidics, and alternative protein scaffolds
0920: Miss Lucka Bibic
School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, United Kingdom
Discovery of a small molecule toxin with inhibitory activity at human P2X4 ion channels
0935: Dr Cassandra Modahl
Department of Biological Sciences, National University of Singapore, Singapore
Rear-fanged snake venom novelty: Adaptive toxicity and metalloproteinase activity
Hamish Ogston Foundation Lecture
0955: Professor José María Gutiérrez
Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica
Unraveling the mechanisms of action of hemorrhagic toxins of viperid snake venoms
1035: Refreshment Break, poster and networking
Session 2: Venoms and toxins: evolution, effects and functions – Chair Professor Dietrich Mebs
1105: Professor Denise Tambourgi
Immunochemistry Laboratory, Butantan Institute, São Paulo, SP, Brazil
Complement system inhibition as means for controlling inflammation associated to envenomation
1125: Dr Sebastien Dutertre
Institut des Biomolécules Max Mousseron, Université Montpellier – Centre Nationale de la Recherche Scientifique, Montpellier, France
Evolutionary considerations on separate predatory and defensive venoms
1145: Dr Timothy Jackson
Australian Venom Research Unit, Department of Pharmacology & Therapeutics, University of Melbourne, Australia
Venom in context: evolution, ecology and snakebite
1205: Miss Chloe Evans
Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Liverpool , United Kingdom
Medically important African snakes cause variable acute phase and inflammatory responses following envenoming (12+3)
1220: Life-time achievement award – Professor Alan Harvey
1230: Group Photo and Lunch
Session 3: Drugs from Toxins – Chair Professor Juan Calvete
1330: Professor Alan Harvey – keynote
Strathclyde University, Glasgow, United Kingdom
Drugs from toxins? Some dos and don’ts?
1400: Professor Glenn King
Institute for Molecular Bioscience, The University of Queensland, St Lucia, Australia
Venom peptide inhibitors of acid-sensing ion channel 1a for treating ischemic injuries of the heart and brain
1420: Dr Elaine Fitches
School of Biosciences, Durham University, South Road, Durham DH1 3LE, United Kingdom
Demonstrating the potential of a novel spider venom based biopesticide for target-specific control of the small hive beetle, a serious pest of the European honey bee
1440: Dr Keith Miller
Biomolecular Sciences Research Centre, Sheffield Hallam University, Sheffield, United Kingdom
Improving the Therapeutic Index of Venom Derived Antimicrobial Peptides
1500: Professor Jan Tytgat
Toxicology and Pharmacology, KU Leuven, Leuven, Belgium
Beyond hemostasis: a potassium channel blocker snake venom serine protease with potential antitumor activity
1520: Mr Ernesto Pinheiro-Junior
School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Brazil
PEGylating toxins: a new trend in toxinology? A successful example of a PEGylated snake venom serine protease
1535: Mr Steve Peigneur
Toxicology and Pharmacology, KU Leuven, Leuven, Belgium
The insecticidal wasp toxin γ–pompilidotoxin is a linear peptide modulating voltage-gated sodium channel
1550: Dr Aneesh Karatt-Vellatt
IONTAS Ltd, Iconic Park, London Road, Pampisford, Cambridge, UK
KnotBodies: Fusing venom derived mini-proteins to antibody CDR loops to treat ion channel mediated pathologies
1610: Refreshment Break, poster and networking
Session 4: Inspiration, Innovation and Investment in Snake-bite Research – Chair Professor David Warrell
1630: Dr Bernadette Abela-Ridder and Dr David Williams, World Health Organization, Switzerland
1700: Professor Mike Turner, The Wellcome Trust, United Kingdom
1720: Professor José María Gutiérrez and Professor Juan Calvete, Global Snakebite Initiative
1730: Dr Cathy Roth, Department for International Development, United Kingdom
1750: Dr Michael Vaughan, Hamish Ogston Foundation, United Kingdom
1805: Dr Benjamin Waldmann, Health Action International, Netherlands
1820: Dr Tamar Ghosh, Royal Society of Tropical Medicine and Hygiene, United Kingdom
1830: End of Day 1
1915: Networking Dinner (by prior booking or invitation only)
Day 2: 29th August
Session 5: Newly Recognised Venomous Taxa – Chair Professor Alan Harvey
0830: Professor Dietrich Mebs – keynote
Institute of Legal Medicine, Goethe-University of Frankfurt, Frankfurt, Germany
What is cheaper: synthesis or acquisition of toxins from exogenous sources?
0900: Dr Ronald Jenner
Department of Life Sciences, Natural History Museum, Cromwell Road, London, United Kingdom
There is no such thing as ‘centipede venom’ – comparative proteotranscriptomic analyses uncover deep divergence of venom composition in Chilopoda
0920: Dr Christopher Lynch
RDM Division of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom
A knottin scaffold directs CXC-chemokine binding specificity of tick evasins
0940: Mr James Dobson
Venom Evolution Lab, School of Biological Sciences, University of Queensland, St. Lucia, Australia
Anguimorph lizard venoms disrupt the clotting ability of human fibrinogen via destructive cleavage
0955: Mr Jonas Krämer
Institute for Zoology, University of Cologne, Cologne, Germany
Venom collection and analysis in the pseudoscorpion Chelifer cancroides
1010: Mr Bjoern Marcus von Reumont
LOEWE Centre for Translational Biodiversity Genomics (LOEWE-TBG), Senckenberganlage, Frankfurt, Germany
Comprehensive insights into the venom system and the genomic processes of toxin evolution in robber flies (Asilidae, Diptera)
1030: Refreshment Break, poster and networking
1050: Professor Paul Long
King’s College London, London, United Kingdom
Is the cnidarian parasite of caviar, ‘Polypodium hydriforme’, a venomous animal?
1110: Dr Gary Bucciarelli
Department of Ecology and Evolutionary Biology, University of California, Los Angeles, USA
Assessing rangewide variation of toxin defenses in a poisonous amphibian
Session 6: Bacterial Toxins – Chair Professor Jan Tytgat
1130: Professor Oliver Dolly
The International Centre for Neurotherapeutics, Lonsdale Building, Dublin City University, Glasnevin, Dublin, Ireland
A chimeric botulinum neurotoxin unveiled that TNFα–induced surface trafficking of TRP/V1 and /A1 channels in sensory neurons is dependent on SNAP-25
1150: Dr John Barr
Centers for Disease Control and Prevention, Atlanta, GA, USA
Comprehensive characterization of anthrax toxins during the course of inhalation infection in non-human primate models
1210: Dr Suzanne Kalb
Centers for Disease Control and Prevention, Atlanta, GA, USA
Mass Spectrometric Detection and Characterization of Botulinum Neurotoxins
1230: Dr Celia Carlini
Brain Institute and School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil
Proteus mirabilis urease: unsuspected non-enzymatic biological properties relevant to pathogenesis
1250: Lunch and networking
Session 7: Monoclonal Antivenoms – Chair Professor José María Gutiérrez
1340: Dr Andreas Laustsen
Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark
Discovery strategies for recombinant antivenoms based on broadly-neutralizing recyclable human monoclonal antibodies
1400: Dr Paddy Waters
Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford, United Kingdom
A snake in the test
1420: Miss Charlotte Dawson
Center for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
Cross-Species and Geographic Potential of Epitope Strings Identified for Generation of an Africa-specific Snake Venom-induced Necrosis Serotherapy
1435: Mrs Nessrin Alomran
Center for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
The immunological cross-reactivity and in vitro neutralising efficacy of novel antivenoms against haemotoxic snake venoms
Session 8: Clinical Toxinology – Chair Dr David Williams
1450: Dr Naira Ayvazyan
Orbeli Institute of Physiology of the National Academy of Sciences, Yerevan, Armenia
Macrovipera lebetina obtusa: Venomics, Bioactivity and Preclinical Assessment of new ovine antivenom (Armenia)
1510: Refreshment Break, poster and networking
1530: Professor Abdulsalami Nasidi
University of Africa, Toru-orua, Bayelsa State, Nigeria
EchiTAb antivenom – A global solution to a local problem
1550: Dr Aniruddha Ghose
Chittagong Medical College & Hospital, Chittagong, Bangladesh
Coagulopathy in Green Pit Viper bite in Bangladesh: an unrecognized and unaddressed issue
1610: Dr Andrew Watt
Australian Venom Research Unit, Department of Pharmacology & Therapeutics, University of Melbourne, Australia
PNG Snakebite Partnership: Antivenom distribution and snakebite incidence across Papua New Guinea
1630: Professor David Warrell
Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom
Myanmar Snake-bite Project: an Australian DFAT-GPFD programme
1650: Dates of the next meeting
1700: Discussion and close
