Provisional Agenda
(subject to change)
Monday 01 April 2019 | St Edmund Hall | Oxford, UK
1030-1110: Registration, welcome coffee and networking
1110: Welcome and housekeeping
Session 1: Chemistry and catalysis
Chair Dr Simon Richardson
1115: Professor Tom Brown and Dr Ysobel Baker, University of Oxford, Oxford, UK
Studies on Oligonucleotides with Chemically Modified backbones
1215: Dr Alexander Taylor, MRC Laboratory of Molecular Biology, Cambridge, UK
Towards versatile RNA endonuclease XNAzymes with catalytic activity in physiological conditions
1245: Dr Marcel Hollenstein, Institut Pasteur, Paris, France
Modified nucleoside triphosphates: versatile tools in chemical biology
1315: Lunch break, posters and exhibition
1400: Mr Simon Chi-Chin Shiu, The University of Hong Kong, Hong Kong, PR China
Signal Enhancement by Aptamer-Enabled DNA Polyhedra and Lattices
1420: Miss Bahareh Amirloo, University of Manchester, Manchester, UK
Towards catalytic turnover: bulge-loop inducing peptidyl-oligonucleotide conjugates for irreversible cleavage of RNA
Session 2: IP & Delivery
Chair Dr Tom Brown
1440: Dr Alison Gallafent, Harrison Goddard Foote (HGF), York, UK
SiRNA and Patents
1500: Dr Simon Richardson, University of Greenwich, London, UK
Exosomes: A Potential siRNA, Antisense And Gene Editing Delivery Platform
1530: Networking Break, posters and exhibition
1600: Professor Rula Zain, Karolinska University Hospital, Sweden
Title TBA
1630: Dr David Evans, Sirnaomics, USA
SiRNA delivery to the liver for therapeutics to treat Fibrosis and Cancer
1700: Dr Ana Paula Pêgo, INEB & i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal
Nucleic acid delivery to the nervous system: breaking barriers exploring nanobiomaterials to promote neuroprotection and neuroregeneration
1730: Dr Pedro MD Moreno, INEB & i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal
In situ delivery of LNA gapmers for gene silencing in spinal cord injury
1750: Dr Patrick Baril, Centre de Biophysique Moléculaire, CNRS UPR4301, Université d’Orléans, Orléans, France
Locoregional delivery and monitoring of miRNA activity in orthotopic model of glioblastoma using a genetic switch luciferase expression system, RILES
1810: Close
1900: Networking dinner (by prior booking or invitation only)
Tuesday 02 April 2019 | St Edmund Hall | Oxford, UK
Session 3: Delivery, and Therapeutic and diagnostic applications
Chair Professor Mike Cheetham
0900: Dr Andrea Masotti, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy
Regulation of angiogenesis through the efficient delivery of microRNAs into endothelial cells using polyamine-coated carbon nanotubes and bidimensional buckypapers
0930: Dr Sylvain Ladame, Imperial College London, London, UK
Early prediction and monitoring of preterm birth: Toward a new paper-based blood test based on detection of highly specific microRNA biomarkers
1000: Dr Haiyan Zhou, University College London, London, UK
Antisense oligonucleotides therapy for COL6-related congenital muscular dystrophy
1030: Networking Break, posters and exhibition
Session 4: Therapeutic and diagnostic applications (contd)
Dr Sylvain Ladame
1100: Professor Peter Zammit, King’s College London, London, UK
Use of antisense oligonucleotide-mediated exon-skipping to remove an exon containing a pathogenic missense mutation: a potential therapy for certain laminopathies?
1130: Dr Mike Cheetham, UCL Institute of Ophthalmology, London, UK
Using iPSC organoid models to develop antisense therapies for inherited retinal disease
1200: Ms Sameen Yousaf, University of Manchester, Manchester, UK
Self-assembling peptide hydrogels: development of 3D nano-biosensor for sequence specific detection of nucleic acids
1220: Close