Provisional timetable
(Subject to change)
Venue: The Jarvis Doctorow Hall, St Edmund Hall, Queen’s Lane, Oxford, UK
Time Zone: All times mentioned refer to British Standard (BST) – London/GMT +01:00.
World Time Converter: https://www.worldtimebuddy.com
NB: Due to the hybrid nature of the agenda and the wide geographical locations of our speakers, it may not have always been possible to group together related presentations.
DAY 1: Monday 04th September
0800: Registration and welcome coffee
0850: Welcome and housekeeping
Session 1: Phage therapy – Chairs Professors Martha Clokie and Chloe James
0900: Professor Jonathan Iredell (Keynote)
Sydney Medical School, Centre for Infectious Diseases and Microbiology and Westmead Hospital, The University of Sydney, Sydney, Australia
Phage therapy in Australia
0930: Professor Martha Clokie (Conference Chair)
Department of Genetics and Genome Biology, University of Leicester, Leicester, UK
Getting phages closer to clinical development; urinary tract infections as an important need
1000: Dr Joseph Campbell
Research Resources Section, Office of Biodefense, Research Resources and Translational Research/DMID/NIAID, Bethesda, MD, USA
NIAID interest in and support for phage therapy
1020: Dr Mariam Dadiani
Eliava Phage Therapy Center (EPTC), Tbilisi, Georgia
Retrospective review of bacteriophage treatment at the Eliava Phage Therapy Center
1040: Refreshment break, networking and posters
1110: Professor Rob Lavigne
Laboratory of Gene Technology, KU Leuven, Leuven, Belgium
Harvesting SynBio parts from phages for tailored expression systems on non-model hosts
Public engagement
1130: Professor Chloe James
School of Science Engineering and Environment, University of Salford, Manchester, UK
Microbial Puppet Masters: immersive SciArt installations and activities to inspire wider public conversations about bacteriophages
Session 2: Molecular and structural biology – Chairs Professors Martha Clokie and Chloe James
1150: Dr John Chen
Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
The life cycles of mobile genetic elements redefined by lateral cotransduction
1210: Mr Pattanai Konpetch
Department of Biochemistry, Faculty of Science, Mahidol University, Ratchathewi, Bangkok, Thailand
Identification and characterization of phage depolymerases encoded from a Clostridioides difficile phage
1230: Dr Willames Martins
Ineos Oxford Institute, Department of Biology, University of Oxford, Oxford, UK
PhageLimp: An interventional study using bacteriophages to combat the AMR dissemination in hospitals from Brazil
1250: Lunch (college dining hall) and networking
1350: Dr Kavya Clement
Centre for Medicines Discovery NDMRB, Old Road Campus, Roosevelt Dr, Headington, Oxford, UK
Multi-level characterization of bacteriophage T5 capsids and capsid-like particles using mass spectrometry
1410: Dr Nikoline Olsen
Department of Plant and Environmental Sciences, University of Copenhagen, Copenhagen, Denmark
dPreQ0 dna modifications in a novel Queuovirinae lineage of Pseudomonas aeruginosa phages provide protection against restriction and CRISPR Cas9 in vitro
1430: Professor Irmtraud Meyer
Laboratory of Bioinformatics of RNA Structure and Transcriptome Regulation, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany
A pipeline for direct RNA sequencing of bacterial transcriptomes
1450: Dr Matthew Dunne
Institute of Food Nutrition and Health, ETH Zürich, Switzerland
A two-pronged attack! Engineering bacteriophages to produce and release heterologous antimicrobial effectors
1510: Dr Enrique González-Tortuero
School of Science, Engineering, and Environment (SEE), University of Salford, Salford, Greater Manchester, UK
After midnight: Pseudomonas aeruginosa and their “Gremlins” the LES prophages
1530: Refreshment break, networking and posters
1600: Dr Sahan Liyanagedera
Synthetic Biophysical Systems Group, Laohakunakorn Lab, Institute of Quantitative Biology Biochemistry and Biotechnology, University of Edinburgh, Edinburgh, UK
SpyPhage: a cell free transcription/translation platform for rapid engineering of targeted phage therapies
Session 3: Food and biotech – Chair Professor Hanne Ingmer
1620: Dr Olivia McAuliffe (V)
Teagasc Food Research Centre, Moorepark, Cork, Ireland
Targeting Listeria monocytogenes with phage-derived proteins
1640: Miss Victoria Harman-McKenna
De Buck Lab, Department of Production Animal Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada
Discovery and application of eight novel phages to protect dairy calves against Johne’s disease
1700: Professor Thomas Sicheritz-Pontén
Center for Evolutionary Hologenomics, The Globe Institute, University of Copenhagen, Denmark
Unfolding the phage world – tales from 4 million phage protein structures
Session 4: Phage-host Interactions – Chair Professor Hanne Ingmer
1720: Professor Heather Allison
Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK
Prophages, what are they doing in that genome?
1740: Close of Day1
1900: Networking dinner – The College dining hall (by prior booking or invitation only)
DAY 2: Tuesday 05th September
Session 4: Phage-host Interactions – Chairs Professors Martha Clokie and Chloe James
0900: Dr Jeremy Barr (V)
Bacteriophage Biology Research Group, Centre to Impact Antimicrobial Resistance, School of Biological Sciences, Monash University, Clayton, Australia
Temperate phages of the human gut
0920: Professor Hanne Ingmer
Food Safety and Zoonosis, Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark
Quorum sensing in Staphylococcus aureus impacts phage susceptibility
0940: Dr Carolin Wendling
Department of Environmental Systems Science, Institute of Integrative Biology, ETH Zürich, Zürich, Switzerland
Prophage maintenance is determined by environment-dependent selective sweeps rather than mutational availability
1000: Dr Somenath Bakshi
Department of Engineering, University of Cambridge, Trumpington Street, Cambridge, UK
Single-cell kinetics of phage infection in bacteria
1020: Refreshment break, networking and posters
1050: Miss Celia Ferriol-González
Instituto de Biología Integrativa de Sistemas, Universitat de València-CSIC, Paterna, Spain
Host range expansion for Klebsiella phage cocktails: a new training method
1110: Dr Claudia Igler
Division of Evolution, Infection and Genomics, The University of Manchester, Manchester, UK
The dependence of phage infection efficacy on bacterial physiology
1130: Professor Andrzej Górski (Keynote) (V)
Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland
Phage repurposing: a futuristic (albeit non-traditional) application of bacterial viruses?
Session 5: ECR symposium – Chairs Drs Rama Bhatia and Rosanna Wright
1200: Dr Rosanna Wright
Division of Evolution, Infection and Genomics, University of Manchester, Oxford Road Campus, Manchester, UK
Can rational design of phage cocktails limit resistance evolution?
1220: Dr Revathy Krishnamurthi
Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences (IVES), University of Liverpool, Liverpool, UK
Prophage mediated rewiring of gene expression landscapes in Pseudomonas aeruginosa
1240: Dr Cédric Lood
Department of Biosystems, KU Leuven, Leuven, Belgium
Modelling the susceptibility of Pseudomonas aeruginosato phages at the strain level
1300: Lunch break, networking and posters
1340: Mr Matthew Thomas
Michael Smith Building, University of Manchester, Dover St, Manchester, UK
Unravelling phage invasion dynamics: modelling and experimental perspectives
1400: Mr Lucas Mora-Quilis
Institute for Integrative Biology Systems (I2SysBio), University of Valencia-CSIC, Paterna, Spain
Study of phage combinations delaying phage resistance in K. pneumoniae
1420: Dr Eleri Ashworth
Department of Clinical infection, Microbiology and Immunology, University of Liverpool, UK
Phage therapy re-sensitises carbapenem resistant Pseudomonas aeruginosa infection to antibiotics in vivo
1440: Miss Sarah Walsh (V)
Centre for Ecology and Conservation; Faculty of Environment, Science, and Economy, Biosciences, University of Exeter, Cornwall, UK
The evolutionary determinants of bacteriophage infectivity
1500: Dr Jason Gill (V)
Department of Animal Science and Faculty of Genetics, Associate Director, Center for Phage Technology, Presidential Impact Fellow, Texas A&M University, College Station, TX, USA
Engineering and adaptation of the temperate Burkholderia phage Milagro
1520: Closing remarks by Professor Clokie, discussion and close