Posters Information and Accepted Posters
Thank you for considering to present your work as a poster at Influenza 2016.
Please prepare your poster in A1 portrait format (59cm wide x 84cm long). Please do not laminate your poster or use heavy printing material. Further information about poster sizes can be found on the following link:
Posters larger than A1 will only be displayed subject to the availability of space.
Maximum capacity 20 A1 potrait posters
Please ensure you have appropriate permissions for the publication of your abstract from the original copyright holders. Should you wish your abstract not to be published, please notify us in writing at the time of abstract submission.
Poster presenters will be required to send us their poster as PDF at least two weeks before the event. The posters will be made available via the event website or other electronic media after the event (see copyright terms).
>>Where can I print my poster in Oxford?
Posters will be displayed for the full duration of the conference. Titles of accepted poster abstracts will be displayed below.
Accepted posters
(Presenters in Bold)
If your abstract has been accepted for presentation but it does not appear in the list below, please let us know as soon as possible by email on FluOxford@gmail.com.
Membrane biophysical properties of influenza viruses in virus infectivity
Stephen P Dunham, Cyril Rauch, Lamyaa Al-Dalawi
School of Veterinary Medicine and Science, University of Sutton Bonington Campus, Nottingham, College Road LE12 5RD
The influenza virus is an enveloped virus possessing a lipid envelope derived from the host cell membrane. It uses a cellular lipid and lipid signal mechanism for entry into the host cell; in addition, lipids play a role in the late stage of the virus lifecycle, assembly and budding. The main purpose of this study is to investigate the molecular and biophysical importance of these lipids in terms of infectivity by pre-treating avian influenza virus…
Codon and clade specific positive selection acting on mammalian Interferon-Induced Transmembrane Proteins
Camilla T O Benfield1, Sarah E Smith2,7, Edward Wright4, Nigel J Temperton5, Boon H Teo1, Paul Kellam2,3,7, Edward C Holmes 6
1 Department of Pathology and Pathogen Biology, The Royal Veterinary College, Hatfield, UK
2 Previous address: The Wellcome Trust Sanger Institute,
The Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
3 Imperial College London, UK
4 Viral Pseudotype Unit (Fitzrovia), Faculty of Science and Technology, University of Westminster, London, UK
5 Viral Pseudotype Unit (Medway), School of Pharmacy, University of Kent, Chatham Maritime, Kent, UK
6 Marie Bashir Institute for Infectious Diseases & Biosecurity, Charles Perkins Centre, School of Biological Sciences and Sydney Medical School, The University of Sydney, Australia
7 Kymab Ltd, Babraham Research Campus, Cambridge, UK
Human and mouse IFITM3 reduce influenza induced morbidity and mortality, and belong to the family of Interferon-induced Transmembrane proteins (IFITMs), host antiviral restriction factors which possess broad-spectrum antiviral activity. We recently reported that IFITM3 from the microbat Myotis myotis is also an endosomal restriction factor which inhibits cell entry by a range of zoonotic viruses including all influenza A virus subtypes tested…
Enhanced early warning systems for notifiable avian disease and the detection of two incursions of LPAI in poultry in the UK
Scott M. Reid1, Jane Clark1, Alejandro Núñez2, Amanda Seekings1, Marek J. Slomka1, Sahar Mahmood1, Jill Banks1, Sharon M. Brookes1, Ian H. Brown1
1 Department of Virology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey, KT15 3NB, United Kingdom
2 Department of Pathology, Animal and Plant Health Agency-Weybridge, Woodham Lane, New Haw, Addlestone, Surrey, KT15 3NB, United Kingdom
Avian influenza (AI) viruses are primarily of low pathogenicity (LP) with a natural reservoir in wild birds. These viruses, which include notifiable H5 and H7 viruses of low pathogenicity, cause mild clinical signs in poultry. The notifiable avian disease (NAD) ‘testing to exclude’ (TTE) scheme was launched by the Animal and Plant Health Agency in 2014 to enable Veterinary Surgeons to carry out AI (and Newcastle Disease) differential diagnosis…
Influenza virus sensitivity to interferon-induced antiviral state depends on pH optimum of hemagglutinin-mediated membrane fusion
Thomas Gerlach1, Luca Hensen1, Tatyana Matrosovich1, Janina Wolf1, Michael Winkler2, Friedemann Weber3, Hans-Dieter Klenk1, Stefan Pöhlmann2, Mikhail Matrosovich1
1 Institute of Virology, Philipps University, Marburg, Germany
2 DPZ, Göttingen, Germany
3 Institute of Virology, Justus-Liebig University, Gießen, Germany
Replication and pathogenicity of influenza viruses critically depend on their ability to tolerate the type I interferon (IFN) antiviral response, however, role of different viral proteins in IFN evasion is not fully defined. Here we studied the role of viral hemagglutinin (HA) using 2:6 PR8-based recombinant viruses with HAs and NAs of representative avian, zoonotic and human viruses. Analyses of infection inhibition in…
Human annexin A6-dependent down regulation of M2 is responsible for restriction of influenza A virus morphogenesis
Maria J. Ramos1, Stefan D. Gaisenband1, Ashley Howkins2, Alan Reynolds2, Béatrice Nal1
1 Virus-Host Interactions Lab, Division of Biosciences, Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge UB8 3PH, UK
2 Experimental Techniques Centre, Brunel University London, Uxbridge UB8 3PH, UK
Despite enormous progress in influenza related research, major host-pathogen interactions regulating influenza A virus (IAV) life cycle still remain poorly understood. Influenza’s integral membrane protein M2 is an essential protein for the virus. M2 proton channel activity is involved in virus uncoating at early stages and inhibition of premature activation of haemagglutinin (HA) envelope protein during its transport to the plasma membrane at later stages. M2 is implicated in membrane curvature at the neck of budding virions, scission and release of progeny viral particles…
Molecular characterization of field and chicken-passaged H9N2 AIV isolates
Edyta Świętoń, Monika Olszewska-Tomczyk, Zenon Minta, Krzysztof Śmietanka
Department of Poultry Diseases, National Veterinary Research Institute, Puławy, Poland
The aim of the present study was molecular characterization of H9N2 avian influenza isolates from field outbreaks in turkeys in Poland during 2013-2014, and the analysis of mutations emerging in the genome of H9N2 isolate from the index case following experimental passages in chickens. Three H9N2 isolates (one from 2013 and two from 2014) were subjected to Sanger sequencing in order to obtain full gene segments or their substantial portions…
Therapeutic administration of broadly neutralising FI6 antibody in pig influenza virus infection
Sophie Morgan1, Hanneke Hemmink1, Barbara Holzer1, Francisco J. Salguero2, Emily Porter3, Gloria Agatic4, Elisabetta Cameroni4, Bryan Charleston1, Davide Corti4, Elma Tchilian1
1 The Pirbright Institute, Woking, Surrey GU24 0NF, UK
2 School of Veterinary Medicine, University of Surrey, Guilford, UK
3 School of Veterinary Sciences, University of Bristol, Langford, UK
4 Humabs BioMed SA, Bellinzona, Switzerland
Influenza A virus is an important zoonotic pathogen that can cause substantial mortality and rapidly disseminate through human and swine populations. Broadly neutralising antibodies against Influenza A viruses (IAV) are a potential therapy and important for vaccine design. FI6 is the first example of a neutralising monoclonal antibody against all IAV, recognizes the hemagglutinin (HA) of all 16 subtypes and neutralizes both group 1 and 2 IAV. Passive transfer of FI6 confers protection to mice and ferrets…
