Provisional Timetable
(subject to change)
All times mentioned refer to British Standard/Summer Time (BST) – London/GMT+01:00. Registered delegates will be sent joining information a few days before the conference.
World Time Converter: https://www.worldtimebuddy.com/
Presentation language: English
Venue: Edward Boyle Auditorium, The Jacqueline du Pré Music Building (JdP), St Hilda’s College, Oxford
Day 1: Wednesday 06th April 2022
1030: Registration and refreshments
1130: Welcome
Session 1: Chair Dr Nebojsa Janjic
1140: Professor Tom Brown
Professor of Chemistry, Department of Chemistry, University of Oxford, Oxford, UK
Oligonucleotide analogues with locked-amide linkages have therapeutic potential
1210: Dr Amy Gelinas
Principal Scientist, SomaLogic Inc, Wilderness Place, Boulder, Colorado, USA
A modified DNA Aptamer mimics viral RNA utilizing a unique molecular recognition strategy with a highly unusual structure
1240: Dr Marcel Hollenstein (V)
Group Leader, Laboratory for Bioorganic Chemistry of Nucleic Acids, Department of Chemistry and Structural Biology, Institut Pasteur, Paris, France
Modified nucleoside triphosphates as tools in chemical biology
1310: Lunch and networking
1400: Professor Francesco Muntoni (V)
Chair of Paediatric Neurology, UCL GOS Institute of Child Health, University College London, UK
Splice switching antisense oligonucleotides in Duchenne Muscular Dystrophy: where are we?
1430: Professor Bruce Sullenger (V)
Joseph W and Dorothy W Beard Distinguished Professor of Experimental Surgery, The School of Medicine, Duke University, Durham, North Carolina, USA
Utilizing SELEX to Identify Novel Functional gRNAS To Probe gRNA Structure-Function Relationships and Expand the Universe of DNA Sequences that can be Efficiently Targeted for Editing
1500: Professor Larry Gold (V) (keynote speaker)
Chairman, SomaLogic and the University of Colorado, Boulder, USA
Broad Proteomics and Target Identification for Pain Therapeutics: Making the Leap from Correlation to Causality
1540: Refreshments and networking
1600: Dr Alex Garanto (V)
Assistant Professor, Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands
Developing of antisense-based therapies for Stargardt disease
1630: Dr James Fink (V)
Senior Principal Scientist, Cell Biology, Q-State Biosciences, Cambridge, MA, USA
Development of an Antisense Oligonucleotide Therapeutic Targeting UBE3A for Dup15q Syndrome
1700: Dr Ashley Jacobi (V)
Senior Scientist, Integrated DNA Technologies, Coralville, Iowa, USA
Streamlined detection of CRISPR editing using the rhAmpSeqTM CRISPR Analysis System
1730: Dr Jonathan Watts (V)
Associate Professor, RNA Therapeutics Institute and Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA
Chemically Modified Guides and Donors for Precision Genome Editing
1800: Close of Day 1
1900: Networking dinner
Day 2: Thursday 07th April 2022
0850: Welcome
0900: Professor Virginia Arechavala-Gomeza (V)
Professor, Neuromuscular Disorders Group, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain
Delivery: a hurdle and the key to nucleic acid therapeutics’ success
0930: Dr Simon Richardson
Reader of Drug Delivery and Membrane Trafficking, Exogenix Laboratory, University of Greenwich, Chatham Maritime, Kent, UK
Quantification of recombinant, attenuated toxin-mediated cytosolic delivery using 32P labelled-siRNA
1000: Dr Jory Lietard
Group Leader, Institute of Inorganic Chemistry, University of Vienna, Althanstraße 14, 1090 Vienna, Austria
Synthesis of complex nucleic acid libraries on microarrays to explore sequence effects at very high throughputs
1030: Refreshments and networking
1100: Dr Jack Wei
Senior Director of Discovery, Sirnaomics Inc, Gaithersburg, MD 20879, USA
mxRNA™: miniaturized RNAi triggers composed of single oligonucleotides
1130: Dr Sylvain Ladame
Reader, Department of Bioengineering, Imperial College London, London, UK
Hydrogel-coated Microneedle Patches for sampling and detection of circulating nucleic acid biomarkers from skin interstitial fluid: Applications for early skin cancer diagnosis
1200: Miss Loukia Petrou
Graduate Researcher, Department of Bioengineering, Imperial College London, London, UK
Engineering of a New Screening Test for the Early Prediction of Preterm Birth Based on microRNA Biomarkers
1220: Miss Britt Hanson
Graduate Researchers, Department of Paediatrics, Medical Sciences Division, University of Oxford, Oxford, UK
Genetic correction of murine muscular dystrophy using CRISPR/Cas9 gene editing and PPMO exon skipping technologies
1240: Dr Edward A Curtis
Group Leader, Institute of Organic Chemistry and Biochemistry, Institute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences, Prague, CZ
Supernova: a deoxyribozyme that catalyzes a chemiluminescent reaction
1300: Discussion and close
